Effects of Natural and Synthetic Estrogens and Various Environmental Contaminants on Vitellogenesis in Fish Primary Hepatocytes: Comparison of Bream (Abramis brama) and Carp (Cyprinus carpio)
نویسندگان
چکیده
منابع مشابه
Effects of primary exposure to environmental and natural estrogens on vitellogenin production in carp (Cyprinus carpio) hepatocytes.
Vitellogenin (vtg) is a precursor of the yolk proteins lipovitelline and phosvitin and is synthesized as a consequence of estrogen-dependent gene expression in female and male hepatocytes of egg-laying vertebrates. Freshly isolated carp hepatocytes of a genetically uniform strain of adult male carp (Cyprinus carpio) were used to investigate the effects of primary exposure to estrogenic compound...
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The efficacy of estrogenic chemicals and plant materials were assessed to stimulate the vitellogenin (VTG) synthesis in an in vitro system based on primary cultures of hepatocytes from female and E2-primed male Mozambique tilapia, Oreochromis mossambicus. Isolated hepatoyctes treated with nonylphenol (NP), bisphenol-A (BP), octylphenol (OP), hexachlorocyclohexane (HCH) and the combination (ALL)...
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ژورنال
عنوان ژورنال: Toxicological Sciences
سال: 2004
ISSN: 1096-0929
DOI: 10.1093/toxsci/kfh176